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The effect of the microinjection of adenosine or its analogs (adenosine 5′-O-(3-thiotriphosphate), adenosine 5′-O-(2-thiodiphosphate), cyclic adenosine monophosphate and 2′-chloroadenosine 5′-O-(3-thiotriphosphate)) into the nucleus tractus solitarii on the reinforcing properties of glucose and a glucose-sucrose mixture were investigated in the thirsty rat. The microinjection of adenosine (30 nmol) into the nucleus tractus solitarii elicited a significant decrease in the intake of the sucrose solution, whereas injection of adenosine 5′-O-(2-thiodiphosphate) (10 nmol) induced a significant increase in the intake of the sucrose solution. Similar effects were obtained when the animals were microinjected with 2′, 3′-cyclic adenosine monophosphate (10 nmol). However, the injection of cyclic adenosine monophosphate and adenosine 5′-O-(3-thiotriphosphate) (10 nmol) did not modify the intake of the glucose-sucrose mixture. The results obtained in the nucleus tractus solitarii show that adenosine, acting through the activation of adenylate cyclase, may be involved in the modulation of the reinforcing properties of tastants.30 days of fieldwork …
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We all know that Japan is on the brink of a digital revolution. Not only are Japanese consumers spending more time online, but the rise of the smartphone is driving this shift.
According to YouGov’s 2014 smartphone survey, smartphones are now used by almost half of the adult population in Japan. In just 4 years, the smartphone penetration rate has increased by almost 4 times and now at 56%, the smartphone is nearly as ubiquitous in Japanese life as the radio was in the 1930s.
This is great news for startups in the Internet of Things (IoT) space. Almost every household in the world has at least one connected IoT device. And the increasing customer appetite for connected devices and services in Japan is leading to a corresponding surge in demand.
However, there are several factors that are preventing Japan’s IoT startup sector from scaling up to the full potential. It’s good to have some perspective when we talk about the market and demand for IoT, as there are some good reasons why Japanese consumers are not at the forefront of the IoT revolution.